Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

About Us

Research

Study & Careers


News

View more

Klára Vokáčová has been awarded the Otto Wichterle Award

Award Published on 12. 06. 2025 Reading time: 2 minutes

Why do brain cancer cells steal mitochondria? New research by IBT CAS and IEM CAS reveals the metabolic dependence of cancer cells

PublicationResearch Published on 28. 05. 2025 Reading time: 3 minutes

A new TUBE study shows that the impact of diesel emissions on brain cells depends on the engine technology

PublicationResearch Published on 26. 05. 2025 Reading time: 2 minutes

A new study from the EXREGMED project shows that stem cell pre-treatment can fundamentally affect their properties

PublicationResearch Published on 23. 05. 2025 Reading time: 1 minute

An international research team of the GIANT project analysed air quality in a Prague high school

ProjectResearch Published on 30. 04. 2025 Reading time: 2 minutes

PhD student Monika Kubísková is the first female scientist to compete in the final ten of Miss Czech Republic 2025

Other Published on 25. 04. 2025 Reading time: 2 minutes
View more

Events

04. 12. 2025

Institutional Seminar Series 12/2025

Professional EventsSeminar
View more

About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Euro-BioImaging, Czech-BioImaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2021-2022 (pdf, 46372 kB)
  • 1975 Established
  • 219 Employees
  • 46 Projects
  • 86 Publications (2024)

Research Departments and Centres

View more

Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Department of Toxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

Department of Cellular Neurophysiology

Research Department

Head of the Department

Miroslava Anděrová

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of Molecular Biology of Cancer

Research Department

Head of the Department

Veronika Vymetálková

View more

Latest Publications

View more

The role of cytokine licensing in shaping the therapeutic potential of wharton's jelly MSCs: metabolic shift towards immunomodulation at the expense of differentiation

 Department of Neuroregeneration Department of Toxicology and Molecular Epidemiology AutořiRohulska O.Vavřinová E.Vackova I.Havelková J.Gotvaldova K.Abaffy P.Kubinova S.Šíma M.Rössner P.Bacakova L.Jendelová P.Smolkova K.Petrenko Y. Published on 2025 Metadata Stem Cell Res Ther . 2025 Apr 20;16(1):199. doi: 10.1186/s13287-025-04309-2.

Hyperactive delta isoform of PI3 kinase enables long-distance regeneration of adult rat corticospinal tract

 Department of Neuroregeneration Department of Auditory Neuroscience AutořiKárová K.Polčanová Z.Knight L.Suchánková S.Nieuwenhuis B.Holota R.Herynek V.Urdzíková-Machová L.Tureček R.Kwok J.C.F.Herik J. vdVerhaagen J.Eva R.Fawcett J.Jendelová P. Published on 2025 Metadata Mol Ther. 2025 Feb 5;33(2):752-770. doi: 10.1016/j.ymthe.2024.12.040. Epub 2025 Jan 1.

Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety

 Department of Auditory Neuroscience AutořiPérez-Garci E.Pysanenko K.Rizzi G.Studer F.Ulrich D.Fritzius T.Früh S.Porcu A.Besseyrias V.Melichar A.Gassmann M.Barkat T. R.Tureček R.Tan K. R.Bettler B. Published on 2025 Metadata Neurobiol Dis. 2025 Feb 4:206:106831. doi: 10.1016/j.nbd.2025.106831. Online ahead of print.

Prophylaxis by a reversible cholinesterase inhibitor and the NMDA receptor antagonist treatment as combinatorial countermeasure against nerve agent poisoning in mice model

 Department of Neurochemistry AutořiKassa J.Konecny J.Svobodova B.Horák M.Korabecny J.Soukup O. Published on 2025 Metadata Chem Biol Interact . 2025 Feb 1:407:111386. doi: 10.1016/j.cbi.2025.111386. Epub 2025 Jan 11.

Perspectives and Limitations of Mesenchymal Stem Cell-Based Therapy for Corneal Injuries and Retinal Diseases

 Department of Toxicology and Molecular Epidemiology AutořiHeřmánková B.Javorková E.Palacká K.Holáň V. Published on 2025 Metadata Cell Transplant . 2025 Jan-Dec:34:9636897241312798. doi: 10.1177/09636897241312798

Topical siRNA therapy of diabetic-like wound healing

 Department of Tissue Engineering AutořiNeuhoferova E.Kindermann M.Buzgo M.Vocetková K.Panek D. Cigler P.Benson V. Published on 2025 Metadata J Mater Chem B . 2025 Jan 15;13(3):1037-1051. doi: 10.1039/d4tb01547a.

Polymorphisms within autophagy-related genes as susceptibility biomarkers for pancreatic cancer: A meta-analysis of three large European cohorts and functional characterization

 Department of Molecular Biology of Cancer AutořiGálvez-Montosa F.Peduzzi G.Sanchez-Maldonado J. M.Horst R. T.Cabrera-Serrano A. J.Gentiluomo M.Macauda A.Luque N.Ünal P.García-Verdejo F. J.Li Y.López J. A. L.Stein A.Bueno-de-Mesquita H. B.Arcidiacono P. G....Vodičková L....Dohan O.Tacelli M.Greenhalf W.Gazouli M.Neoptolemos J. P.Cavestro G. M.Boggi U.Latiano A.Hegyi P.Ginocchi L.Netea M. G.Sánchez-Rovira P.Canzian F.Campa D.Sainz J. Published on 2025 Metadata Int J Cancer. 2025 Jan 15;156(2):339-352. doi: 10.1002/ijc.35196. Epub 2024 Sep 25.

Portable emissions toxicity system: Evaluating the toxicity of emissions or polluted air by exposure of cell cultures at air-liquid interface in a compact field-deployable setup

 Department of Toxicology and Molecular Epidemiology AutořiVojtíšek M.Dittrich L.Pechout M.Červená T.Vimrová A.Sikorová J.Závodná T.Ondracek J.Aakko-Saksa P.Topinka J.Rössner P. Published on 2025 Metadata Sci Total Environ. 2025 Jan 10:959:178010. doi: 10.1016/j.scitotenv.2024.178010. Epub 2024 Dec 21.

The Influence of Asymmetric Hearing Loss on Peripheral and Central Auditory Processing Abilities in Patients With Vestibular Schwannoma

 Department of Auditory Neuroscience AutořiSvobodova V.Profant O.Syka J.Tóthová D.Bureš Z. Published on 2025 Metadata Ear Hear. 2025 Jan-Feb;46(1):60-70. doi: 10.1097/AUD.0000000000001555. Epub 2024 Jul 15.
View more